Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865378 | 0.87 | MAPT (0.55) | HTTHSD17B10MAPTGFERGPR55 | |
| SCHEMBL1796583 | 0.87 | MAPT (0.55) | HTTALDH1A1HSD17B10MAPTGFER | |
| Hydrochloric Acid SCHEMBL27964006 | 0.85 | MAPT (0.52) | HTTALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL5776485 | 0.79 | — | — | |
| SCHEMBL7024646 | 0.79 | — | — | |
| SCHEMBL35226 | 0.79 | — | — | |
| SCHEMBL10704841 | 0.78 | FLT1 (0.47) | ALDH1A1MAPTTSHRALOX15CYP3A4 | |
| SCHEMBL7907022 | 0.78 | MEN1 (0.54) | HTTALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL3695975 | 0.78 | CES2 (0.60) | HTTHSD17B10MAPTGFERGPR55 | |
| SCHEMBL13461740 | 0.78 | MAPT (0.75) | HTTALDH1A1HSD17B10MAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066943-B1 | 1,1-DIPHENYLALKENES AND A PROCESS FOR THEIR PREPARATION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | claimed |
| EP-0066943-A1 | 1,1-Diphenylalkenes and a process for their preparation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-15 | — | — | EP | claimed |