Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704841 | 0.89 | FLT1 (0.47) | TSHRSMN1; SMN2CASP1SRD5A2RAB9A | |
| SCHEMBL28668332 | 0.88 | SMN1; SMN2 (0.52) | TSHRSMN1; SMN2CASP1SRD5A2RAB9A | |
| SCHEMBL10905142 | 0.85 | CA1 (0.42) | TSHRSMN1; SMN2CASP1SRD5A2RAB9A | |
| SCHEMBL9592286 | 0.85 | TSHR (0.44) | TSHRSMN1; SMN2CASP1SRD5A2RAB9A | |
| SCHEMBL2081053 | 0.82 | TSHR (0.48) | TSHRSMN1; SMN2CASP1SRD5A2RAB9A | |
| SCHEMBL9590622 | 0.79 | MEN1 (0.55) | TSHRSMN1; SMN2CASP1SRD5A2RAB9A | |
| SCHEMBL2933370 | 0.79 | RAB9A (0.46) | SMN1; SMN2RAB9AHPGDNPC1KMT2A | |
| SCHEMBL10901306 | 0.78 | KMT2A (0.56) | TSHRSMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL331512 | 0.78 | CA1 (0.52) | TSHRSMN1; SMN2CASP1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL27669623 | 0.78 | RAB9A (0.45) | SMN1; SMN2RAB9AHPGDNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147788-A1 | Stilbene derivatives and their use as aryl hydrocarbon receptor antagonistic ligands | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M.) (FR) | 2004-07-29 | — | — | US | claimed |
| EP-1418164-A1 | New stilbene derivatives and their use as aryl hydrocarbon receptor ligand antagonists | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-05-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147788-A1 | Stilbene derivatives and their use as aryl hydrocarbon receptor antagonistic ligands | AHR, HCAR3, HCAR1 | TSHR 35/4885SMN1; SMN2 4212/4885CASP1 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.