Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068319 | 0.71 | NAPRT (0.77) | TBXAS1NAPRT | |
| Hydrochloric Acid SCHEMBL11059321 | 0.70 | NAPRT (0.74) | TBXAS1NAPRT | |
| SCHEMBL11068577 | 0.69 | TBXAS1 (1.00) | TBXAS1NAPRT | |
| SCHEMBL13403930 | 0.69 | KMO (0.59) | TBXAS1NAPRT | |
| SCHEMBL11067952 | 0.68 | TBXAS1 (0.67) | TBXAS1NAPRT | |
| SCHEMBL727185 | 0.68 | CYP1A2 (0.62) | TBXAS1NAPRT | |
| Hydrochloric Acid SCHEMBL11064866 | 0.68 | TBXAS1 (1.00) | TBXAS1 | |
| Formic Acid SCHEMBL27652252 | 0.68 | TBXAS1 (0.61) | TBXAS1NAPRTCYP3A4 | |
| SCHEMBL10627493 | 0.68 | TBXAS1 (0.54) | TBXAS1NAPRTMEN1TP53CYP3A4 | |
| SCHEMBL11190754 | 0.68 | ADORA2A (0.47) | TBXAS1MEN1TP53CYP3A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103945-B1 | SUBSTITUTED BENZENEDIOLS AND BENZODIOXINS | THE UPJOHN COMPANY (US) | 1988-04-20 | — | — | EP | claimed |
| US-4501892-A | Pyridyl benzenediols | THE UPJOHN COMPANY (US) | 1985-02-26 | — | — | US | claimed |
| EP-0103945-A2 | Substituted benzenediols and benzodioxins | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | claimed |
| EP-0103945-B1 | SUBSTITUTED BENZENEDIOLS AND BENZODIOXINS | THE UPJOHN COMPANY (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4501892-A | Pyridyl benzenediols | THE UPJOHN COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0103945-A2 | Substituted benzenediols and benzodioxins | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | disclosed |