SCHEMBL10705263

SCHEMBL10705263

CC(CCOc1ccc(O)cc1)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 2/20 0.51
DRD3 P35462 2/20 0.51
DRD2 P14416 1/20 0.51
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
LMNA P02545 2/20 0.47
CYP1A2 P05177 2/20 0.47
SLC6A2 P23975 2/20 0.47
CYP2C19 P33261 2/20 0.47
SLC6A3 Q01959 2/20 0.47
HIF1A Q16665 2/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
CYP19A1 P11511 3/20 0.47
ESR1 P03372 2/20 0.45
ESR2 Q92731 2/20 0.45
ESRRB O95718 2/20 0.45
LTA4H P09960 3/20 0.45
NR5A1 Q13285 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1454985 0.90 KCNA3 (0.52) PPARGPPARALMNAPTGS1LTA4H
SCHEMBL10704258 0.83 LMNA (0.55) DRD4DRD3DRD2PPARGPPARA
SCHEMBL10407110 0.82 DRD4 (0.53) DRD4DRD3DRD2PPARGPPARA
SCHEMBL1794831 0.82 GAA (0.51) LMNALTA4HNR5A1MAPK1ALDH1A1
SCHEMBL14196407 0.81 LTA4H (0.44) DRD4DRD3DRD2PPARGPPARA
SCHEMBL8911681 0.78 DRD4 (0.69) DRD4DRD3DRD2LMNACYP1A2
SCHEMBL8432243 0.77 MAPK1 (0.73) MAPK1ALDH1A1KMT2A
SCHEMBL5400573 0.77 MAPK1 (0.73) MAPK1ALDH1A1KMT2A
SCHEMBL27291009 0.77 FFAR1 (0.50) DRD4DRD3DRD2PPARGPPARA
1-Hydroxy-4-Isopentoxybenzene SCHEMBL2843554 0.77 TDP1 (0.66) SLC6A2PTGS1ESR1LTA4HNR5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0167918-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1988-09-14 EP disclosed
US-4633277-A HIGH SPEED; NO FADING OR FOGGING KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1986-12-30 US disclosed
EP-0167918-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1986-01-15 EP disclosed