SCHEMBL10705267

SCHEMBL10705267

CCC(=O)C1=C(O)CC(c2cccc(C)c2C)CC1=O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.46
MAP1LC3B Q9GZQ8 3/20 0.41
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
HTR2C P28335 2/20 0.38
LDHA P00338 2/20 0.36
LDHB P07195 2/20 0.36
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10679232 0.85 LDHA (0.48) RAB9AMAP1LC3BKDM4EGAAMAPT
SCHEMBL9837788 0.81 RAB9A (0.48) RAB9AMAP1LC3BKDM4EGAAMAPT
SCHEMBL10734421 0.80 RAB9A (0.47) RAB9AMAP1LC3BKDM4EGAAMAPT
SCHEMBL9343916 0.77 RAB9A (0.46) RAB9AMAP1LC3BKDM4EGAAMAPT
SCHEMBL9722674 0.77 RAB9A (0.39) RAB9AMAP1LC3BKDM4EGAAMAPT
SCHEMBL10678641 0.76 RAB9A (0.41) RAB9AKDM4EGAAMAPTMEN1
SCHEMBL9343905 0.76 RAB9A (0.44) RAB9AMAP1LC3BKDM4EGAAMAPT
SCHEMBL9345685 0.75 RAB9A (0.53) RAB9AMAP1LC3BKDM4EGAAMAPT
SCHEMBL10683366 0.75 RAB9A (0.40) RAB9AKDM4EGAAMAPTMEN1
SCHEMBL8091912 0.75 RAB9A (0.40) RAB9AKDM4EGAAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0133349-B1 HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES ICI AUSTRALIA LIMITED (AU) 1988-09-21 EP disclosed
US-4652303-A Herbicidal 5-(acylphenyl)cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1987-03-24 US disclosed
EP-0133349-A1 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1985-02-20 EP disclosed