Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | OXTR | P30559 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934549 | 0.88 | OXTR (0.53) | OXTROPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL176484 | 0.82 | TSHR (0.53) | TSHROPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL11160181 | 0.82 | OXTR (0.53) | OXTRMEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL10509212 | 0.82 | LSS (0.41) | TSHROXTROPRM1OPRD1OPRK1 | |
| SCHEMBL11161706 | 0.82 | TSHR (0.45) | TSHROXTRALDH1A1HPGDMEN1 | |
| SCHEMBL9474105 | 0.80 | TSHR (0.48) | TSHROPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL335201 | 0.79 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL334951 | 0.79 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL8711919 | 0.79 | OXTR (0.50) | OXTRAVPR1A | |
| SCHEMBL11331453 | 0.78 | ALDH1A1 (0.47) | TSHRALDH1A1HPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094436-B1 | N-GLYCIDYL-SUBSTITUTED AMIDE COMPOUNDS | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-03-30 | — | — | EP | disclosed |
| EP-0094436-A1 | N-GLYCIDYL-SUBSTITUTED AMIDE COMPOUNDS | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1983-11-23 | — | — | EP | disclosed |