Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461740 | 0.89 | MAPT (0.75) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL7907022 | 0.89 | MEN1 (0.54) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL8618039 | 0.87 | MAOB (0.45) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL10705376 | 0.87 | HTT (0.46) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL13811433 | 0.87 | ACHE (0.62) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL24398858 | 0.83 | BCL2L1 (0.54) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL18689505 | 0.81 | CES2 (0.52) | CES2CES1MAOAMAOBCA1 | |
| SCHEMBL10946523 | 0.80 | MAOA (0.40) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL9208657 | 0.80 | LTA4H (0.52) | MAPTBCL2L1BADRAB9ALTA4H | |
| SCHEMBL10363954 | 0.79 | CES2 (0.50) | CES2CES1MAOAMAOBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197036-A | Method for carrying out anti-Ma hydrocarboxylation reaction on olefin compound and carbon dioxide by photocatalysis | 中国科学院理化技术研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-109265311-B | Phenyl fluorene derivative and preparation method and application thereof | 上海兆维科技发展有限公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-108623425-A | Method for constructing four-membered ring by visible light catalysis [2+2] reaction | 中国科学院理化技术研究所 | 2018-10-09 | — | — | CN | disclosed |
| WO-2017216129-A1 | FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL | MERCK PATENT GMBH (DE) | 2017-12-21 | — | — | WO | disclosed |
| EP-2780326-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | Vivolux Ab (SE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013058691-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2013-04-25 | — | — | WO | disclosed |
| US-5631264-A | NEUROLOGICAL DISORDERS | SANOFI WINTHROP, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5604224-A | NEURODEGENERATIVE DISORDERS | STERLING WINTHROP INC. (US) | 1997-02-18 | — | — | US | disclosed |
| US-5569655-A | Substituted heterocyclylisoquinolinium salts and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1996-10-29 | — | — | US | disclosed |
| US-5554620-A | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof | STERLING WINTHROP INC. (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0656359-A1 | Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts and compositionsand methods of use thereof | STERLING WINTHROP INC. (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0647641-A1 | Substituted heterocyclylisoquinolinium salts and compositions and methods of usethereof | STERLING WINTHROP INC. (US) | 1995-04-12 | — | — | EP | disclosed |
| EP-0065354-B1 | PROCESS FOR THE PREPARATION OF 1,1-BIS PHENYL-2-HALOALKAN-1-OLS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-07-03 | — | — | EP | disclosed |
| US-4431852-A | HALOGENATION OF A 1,1-DIPHENYL ETHANOL OR -ETHENE IN WATER AT A PH OF 7 OR LOWER | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1984-02-14 | — | — | US | disclosed |
| EP-0065354-A1 | Process for the preparation of 1,1-bis phenyl-2-haloalkan-1-ols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-24 | — | — | EP | disclosed |