Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713073 | 0.87 | GAA (0.62) | GAAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL10714402 | 0.82 | GAA (0.43) | GAAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL10713138 | 0.81 | MAPT (0.53) | GAAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL1604941 | 0.80 | GAA (0.73) | GAAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL3099361 | 0.77 | GAA (0.52) | GAAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL5732298 | 0.77 | GAA (0.49) | GAAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL10713757 | 0.74 | ALDH1A1 (0.48) | GAAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL10707773 | 0.73 | ALDH1A1 (0.67) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL10705604 | 0.70 | TSHR (0.46) | GAAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL5082925 | 0.67 | ALDH1A1 (0.50) | GAAMAPK1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202538-B1 | GROWTH PROMOTING AGENTS | BAYER AG (DE) | 1988-12-28 | — | — | EP | disclosed |