Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713073 | 0.87 | GAA (0.62) | ALDH1A1KDM4ETSHRHPGDCYP2C9 | |
| SCHEMBL3639255 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4ETSHRHPGD | |
| SCHEMBL10710912 | 0.80 | CNR2 (0.43) | ALDH1A1HSD17B10KDM4EHPGDGAA | |
| SCHEMBL3242997 | 0.77 | RAF1 (0.38) | ALDH1A1HPGDGAAMAPTKMT2A | |
| SCHEMBL10712552 | 0.77 | RAF1 (0.37) | ALDH1A1HSD17B10KDM4ETSHRHPGD | |
| SCHEMBL1965507 | 0.76 | GAA (0.73) | ALDH1A1HSD17B10KDM4ETSHRHPGD | |
| SCHEMBL10705462 | 0.74 | GAA (0.47) | ALDH1A1HSD17B10KDM4ETSHRHPGD | |
| SCHEMBL22774673 | 0.74 | GABRA1 (0.41) | ALDH1A1CYP1A2CYP2C9GAAMAPK1 | |
| SCHEMBL10717074 | 0.73 | ALDH1A1 (0.64) | ALDH1A1HSD17B10KDM4EHPGDCYP1A2 | |
| SCHEMBL5730997 | 0.73 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4ETSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4692461-A | PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| EP-0224140-A1 | Thienyl urea derivatives | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |