Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | CHKA | P35790 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41501 | 0.88 | SIGMAR1 (0.71) | SIGMAR1LMNAPOLBKMT2A | |
| SCHEMBL1111888 | 0.84 | DRD4 (0.53) | SIGMAR1HRH3FAAHMGLL | |
| SCHEMBL16226080 | 0.84 | SIGMAR1 (0.78) | ALDH1A1TSHRCYP2D6CYP2C19CHKA | |
| SCHEMBL1690956 | 0.82 | CYP2D6 (0.85) | ALDH1A1TSHRCYP2D6CYP2C19CHKA | |
| SCHEMBL42218 | 0.81 | SIGMAR1 (0.61) | ALDH1A1CYP2D6CYP2C19SIGMAR1HRH3 | |
| SCHEMBL24023622 | 0.81 | CYP2D6 (0.89) | ALDH1A1CYP2D6CYP2C19CHKASIGMAR1 | |
| SCHEMBL1997330 | 0.81 | CYP2D6 (0.89) | ALDH1A1CYP2D6CYP2C19CHKASIGMAR1 | |
| SCHEMBL24023625 | 0.81 | CYP2D6 (0.89) | ALDH1A1CYP2D6CYP2C19CHKASIGMAR1 | |
| SCHEMBL1111800 | 0.80 | HTR7 (0.60) | HRH3FAAHMGLL | |
| SCHEMBL27674930 | 0.79 | CYP2D6 (0.61) | ALDH1A1TSHRCYP2D6CYP2C19CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284552-A1 | 4-Benzyl-piperazinyl-hydrazones | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | claimed |
| EP-0284552-A1 | 4-Benzyl-piperazinyl-hydrazones | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | disclosed |