Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.85 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.80 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.80 |
| ▸ | CHKA | P35790 | 2/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24023622 | 0.98 | CYP2D6 (0.89) | CYP2D6CYP2C19HRH3HRH4CHKA | |
| SCHEMBL1997330 | 0.98 | CYP2D6 (0.89) | CYP2D6CYP2C19HRH3HRH4CHKA | |
| SCHEMBL24023625 | 0.98 | CYP2D6 (0.89) | CYP2D6CYP2C19HRH3HRH4CHKA | |
| SCHEMBL16226080 | 0.89 | SIGMAR1 (0.78) | CYP2D6CYP2C19HRH3HRH4CHKA | |
| SCHEMBL1777747 | 0.87 | SIGMAR1 (0.81) | CYP2D6CYP2C19HRH3HRH4SIGMAR1 | |
| SCHEMBL13952 | 0.87 | SIGMAR1 (0.81) | CYP2D6CYP2C19HRH3HRH4SIGMAR1 | |
| SCHEMBL13940572 | 0.86 | CHKA (0.74) | CYP2D6CYP2C19HRH3HRH4CHKA | |
| Ammonia Solution, Strong SCHEMBL3699405 | 0.85 | SIGMAR1 (0.77) | CYP2D6CYP2C19HRH3HRH4SIGMAR1 | |
| SCHEMBL688047 | 0.85 | SIGMAR1 (0.77) | CYP2D6CYP2C19HRH3HRH4SIGMAR1 | |
| SCHEMBL8327 | 0.85 | SIGMAR1 (0.77) | CYP2D6CYP2C19HRH3HRH4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490063-B | Fluoroboron compound, aromatic ring aminomethylating agent comprising the same, and method for producing compound having aminomethyl aromatic ring using the aromatic ring aminomethylating agent | Sanitary Material R&D Management Co.,Ltd. (JP) | 2014-10-22 | — | — | CN | disclosed |
| EP-2039697-B1 | FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING COMPRISING THE COMPOUND, AND PROCESS FOR PRODUCTION OF COMPOUND HAVING AMINOMETHYL-AROMATIC RING USING THE AMINOMETHYLATING AGENT | EISAI R&D MAN CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |
| EP-2039697-B1 | FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING COMPRISING THE COMPOUND, AND PROCESS FOR PRODUCTION OF COMPOUND HAVING AMINOMETHYL-AROMATIC RING USING THE AMINOMETHYLATING AGENT | EISAI R&D MAN CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-8524946-B2 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-8524946-B2 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-8524946-B2 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-20120010403-A1 | FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING MADE OF THE SAME, AND PRODUCTION METHOD OF COMPOUND CONTAINING AMINOMETHYL AROMATIC RING USING AMINOMETHYLATING AGENT | TANAKA KEIGO (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20120010403-A1 | FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING MADE OF THE SAME, AND PRODUCTION METHOD OF COMPOUND CONTAINING AMINOMETHYL AROMATIC RING USING AMINOMETHYLATING AGENT | TANAKA KEIGO (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20120010403-A1 | FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING MADE OF THE SAME, AND PRODUCTION METHOD OF COMPOUND CONTAINING AMINOMETHYL AROMATIC RING USING AMINOMETHYLATING AGENT | TANAKA KEIGO (JP) | 2012-01-12 | — | — | US | disclosed |
| US-8044216-B2 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8044216-B2 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8044216-B2 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-10-25 | — | — | US | disclosed |
| CN-101490063-A | Fluoroboron compound, aromatic ring aminomethylating agent comprising the same, and method for producing compound having aminomethyl aromatic ring using the aromatic ring aminomethylating agent | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| EP-2039697-A1 | FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING COMPRISING THE COMPOUND, AND PROCESS FOR PRODUCTION OF COMPOUND HAVING AMINOMETHYL-AROMATIC RING USING THE AMINOMETHYLATING AGENT | Eisai R&D Management Co., Ltd. (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-2039697-A1 | FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING COMPRISING THE COMPOUND, AND PROCESS FOR PRODUCTION OF COMPOUND HAVING AMINOMETHYL-AROMATIC RING USING THE AMINOMETHYLATING AGENT | Eisai R&D Management Co., Ltd. (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-20080015351-A1 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | EISAI R&D MANAGEMENT CO., LTD. | 2008-01-17 | — | — | US | disclosed |
| US-20080015351-A1 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | EISAI R&D MANAGEMENT CO., LTD. | 2008-01-17 | — | — | US | disclosed |
| US-20080015351-A1 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | EISAI R&D MANAGEMENT CO., LTD. | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015351-A1 | Fluoroboron compound, aminomethylating agent for aromatic ring made of the same, and production method of compound containing aminomethyl aromatic ring using aminomethylating agent | PRMT6, MLLT3, PRMT3 | CYP2D6 412/4885CYP2C19 1522/4885HRH3 224/4885 |
| US-20120010403-A1 | FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING MADE OF THE SAME, AND PRODUCTION METHOD OF COMPOUND CONTAINING AMINOMETHYL AROMATIC RING USING AMINOMETHYLATING AGENT | PRMT6, MLLT3, PRMT3 | CYP2D6 412/4885CYP2C19 1522/4885HRH3 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.