Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127346 | 0.85 | HSD17B14 (0.59) | KMT2AHSD17B14ALDH1A1CES2CES1 | |
| SCHEMBL14594128 | 0.84 | ALOX5 (0.59) | ALOX5PTGS1PTGS2TNFRSF1AGAA | |
| SCHEMBL9135750 | 0.77 | PTGS2 (0.63) | KMT2AALOX5PTGS1PTGS2TNFRSF1A | |
| SCHEMBL10704231 | 0.77 | ALOX5 (0.51) | KMT2AALOX5PTGS1PTGS2TNFRSF1A | |
| SCHEMBL28038453 | 0.76 | KMT2A (0.51) | KMT2AHSD17B14ALDH1A1CES2CES1 | |
| SCHEMBL28038778 | 0.76 | KMT2A (0.66) | KMT2AHSD17B14GAAALDH1A1CES2 | |
| SCHEMBL8088462 | 0.76 | PTGS2 (0.71) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8495448 | 0.76 | ALOX5 (0.65) | KMT2AALOX5PTGS1PTGS2TNFRSF1A | |
| SCHEMBL16473181 | 0.76 | KMT2A (0.60) | KMT2AHSD17B14GAAALDH1A1MEN1 | |
| SCHEMBL12775476 | 0.76 | KMT2A (0.56) | KMT2APTGS2HSD17B14ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094422-B1 | SUBSTITUTED PYRIDINES | RIKER LABORATORIES, INCORPORATED (US) | 1988-08-03 | — | — | EP | claimed |
| US-4414217-A | ANTIINFLAMMATORY | RIKER LABORATORIES, INC. (US) | 1983-11-08 | — | — | US | claimed |
| CN-114149311-B | Method for preparing 4-hydroxybenzophenone compound by taking p-methylene quinone as substrate | 上海应用技术大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-114149311-A | Method for preparing 4-hydroxybenzophenone compound by taking p-methylenequinone as substrate | 上海应用技术大学 | 2022-03-08 | — | — | CN | disclosed |
| EP-0094422-B1 | SUBSTITUTED PYRIDINES | RIKER LABORATORIES, INCORPORATED (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4524210-A | ANTIINFLAMMATORY AGENTS | RIKER LABORATORIES, INC. (US) | 1985-06-18 | — | — | US | disclosed |
| EP-0094422-A1 | SUBSTITUTED PYRIDINES. | RIKER LABORATORIES INC (US) | 1983-11-23 | — | — | EP | disclosed |
| US-4414217-A | ANTIINFLAMMATORY | RIKER LABORATORIES, INC. (US) | 1983-11-08 | — | — | US | disclosed |
| WO-1983001775-A1 | SUBSTITUTED PYRIDINES | RIKER LABORATORIES INC (US) | 1983-05-26 | — | — | WO | disclosed |