Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | SI | P14410 | 5/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ENTPD5 | O75356 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749407 | 0.82 | AKT1 (0.51) | AKT1RXRAMAPTMGAMGAA | |
| SCHEMBL8653315 | 0.78 | AKT1 (0.50) | AKT1RXRAMGAMGAASI | |
| SCHEMBL30513267 | 0.76 | AKT1 (0.56) | AKT1MAPTMGAMGAASI | |
| SCHEMBL3184205 | 0.76 | AKT1 (0.56) | AKT1MAPTMGAMGAASI | |
| SCHEMBL4194290 | 0.75 | AKT1 (0.60) | AKT1RXRAMAPTMGAMGAA | |
| SCHEMBL11705856 | 0.74 | AKT1 (0.55) | AKT1RXRAMAPTMGAMGAA | |
| SCHEMBL5773379 | 0.73 | AKT1 (0.64) | AKT1RXRAMGAMGAASI | |
| SCHEMBL11405269 | 0.72 | AKT1 (0.44) | AKT1RXRAMAPTMGAMGAA | |
| SCHEMBL10708009 | 0.72 | PPARG (0.50) | AKT1ESR1ESR2 | |
| SCHEMBL10636265 | 0.72 | AKT1 (0.47) | AKT1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129906-B1 | PHENOXYALKOXY-3,4-DIHYDRO-2H-1-BENZOPYRAN DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-06-08 | — | — | EP | disclosed |