Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | SI | P14410 | 5/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30513267 | 1.00 | AKT1 (0.56) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL4974003 | 0.86 | ALDH1A1 (0.49) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL31254037 | 0.86 | ALDH1A1 (0.49) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL11705856 | 0.84 | AKT1 (0.55) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL30888534 | 0.82 | MAPT (0.47) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL5546007 | 0.81 | MAPT (0.60) | AKT1GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL7787622 | 0.81 | AKT1 (0.51) | AKT1MGAMGAASIMGAM2 | |
| Formaldehyde SCHEMBL27953583 | 0.81 | ALDH1A1 (0.49) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL9749407 | 0.80 | AKT1 (0.51) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL6849624 | 0.80 | PKM (0.49) | AKT1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3772975-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP Assets B.V. (NL) | 2021-02-17 | — | — | EP | disclosed |
| EP-3774756-A1 | PROCESS FOR THE MANUFACTURE OF CHROMAN-6-OLS WITH SHORT SIDE CHAINS | DSM IP Assets B.V. (NL) | 2021-02-17 | — | — | EP | disclosed |
| US-20210030022-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2021-02-04 | — | — | US | disclosed |
| US-20210030022-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2021-02-04 | — | — | US | disclosed |
| CN-111936483-A | Process for preparing chroman-6-ols having short side chains | 帝斯曼知识产权资产管理有限公司 | 2020-11-13 | — | — | CN | disclosed |
| WO-2019185891-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185900-A1 | PROCESS FOR THE MANUFACTURE OF CHROMAN-6-OLS WITH SHORT SIDE CHAINS | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185900-A1 | PROCESS FOR THE MANUFACTURE OF CHROMAN-6-OLS WITH SHORT SIDE CHAINS | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185894-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185894-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| US-20100028278-A1 | USE OF CHROMAN-4-ONE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-02-04 | — | — | US | disclosed |
| US-6756432-B2 | POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-06-29 | — | — | US | disclosed |
| US-20030153655-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-08-14 | — | — | US | disclosed |
| US-6465548-B1 | 6-HYDROXYCHROMAN DERIVATIVE WITH PHOSPHORUS AND PHENOLIC ANTIOXIDANTS; HEAT, LIGHT AND OXIDATION STABILITY DURING MOLDING | YOSHITOMI FINE CHEMICALS, LTD. (JP) | 2002-10-15 | — | — | US | disclosed |
| US-4207111-A | COUPLERS CAPABLE OF FORMING AZOMETHINE DYES ON COUPLING WITH OXIDATION PRODUCT OF AROMATIC PRUMARY AMINE DEVELOPER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-06-10 | — | — | US | disclosed |
| US-4155765-A | COLORFAST | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-05-22 | — | — | US | disclosed |
| US-4054580-A | Process for producing 2,2,4-trimethyl-6-hydroxy-7-substituted chromans | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-18 | — | — | US | disclosed |
| US-3951664-A | Light-sensitive material having developers embedded therein | AGFA-GEVAERT, A.G. (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951660-A | HETEROCYCLIC TONER COMPOUND | AGFA-GEVAERT, A.G. (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3933507-A | LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER | AGFA-GEVAERT, A.G. (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210030022-A1 | NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS | KMO, FFAR3, ACOX3 | AKT1 1416/4885MGAM 1317/4885GAA 3650/4885 |
| US-20100028278-A1 | USE OF CHROMAN-4-ONE DERIVATIVES | COXFA4L2, TYR, XPA | AKT1 2406/4885MGAM 3590/4885GAA 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.