Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.60 |
| ▸ | MGAM | O43451 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | SI | P14410 | 5/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346909 | 0.88 | AKT1 (0.46) | AKT1RXRABCHENR1I2AKR1B1 | |
| SCHEMBL5773379 | 0.86 | AKT1 (0.64) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL8653315 | 0.78 | AKT1 (0.50) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL5773051 | 0.78 | AKT1 (0.60) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL5846302 | 0.78 | AKT1 (0.60) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL10346642 | 0.77 | AKT1 (0.46) | AKT1RXRABCHEPPARGPPARD | |
| SCHEMBL10636272 | 0.76 | AKT1 (0.58) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL30513267 | 0.76 | AKT1 (0.56) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL3184205 | 0.76 | AKT1 (0.56) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL10706197 | 0.75 | AKT1 (0.47) | AKT1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060141591-A1 | Method for producing optically active chroman-carboxylate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-06-29 | — | — | US | claimed |
| EP-1634958-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CHROMAN-CARBOXYLATE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-03-15 | — | — | EP | claimed |
| EP-1634958-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CHROMAN-CARBOXYLATE | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-20060141591-A1 | Method for producing optically active chroman-carboxylate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-06-29 | — | — | US | disclosed |
| EP-1634958-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CHROMAN-CARBOXYLATE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060141591-A1 | Method for producing optically active chroman-carboxylate | ACMSD, ADH5, ADH1C | AKT1 1956/4885MGAM 20/4885GAA 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.