Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014488 | 1.00 | KMT2A (0.46) | KMT2AHRH3LMNAHRH4GRM2 | |
| SCHEMBL1013773 | 1.00 | KMT2A (0.46) | KMT2AHRH3LMNAHRH4GRM2 | |
| SCHEMBL4268087 | 0.86 | GRM2 (0.47) | KMT2AGRM2HDAC1HDAC6MEN1 | |
| SCHEMBL13674810 | 0.80 | LTA4H (0.52) | KMT2AHRH3HRH4GRM2MAOB | |
| SCHEMBL1013735 | 0.79 | MLYCD (0.40) | KMT2AGRM2HDAC1HDAC6OPRK1 | |
| SCHEMBL1013734 | 0.79 | MLYCD (0.40) | KMT2AGRM2HDAC1HDAC6OPRK1 | |
| SCHEMBL1014953 | 0.79 | MLYCD (0.40) | KMT2AGRM2HDAC1HDAC6OPRK1 | |
| SCHEMBL171824 | 0.78 | KMT2A (0.43) | KMT2AHRH3LMNAMEN1OPRK1 | |
| SCHEMBL4268092 | 0.77 | ALDH1A1 (0.49) | HRH3LMNAHRH4GRM2ALDH1A1 | |
| SCHEMBL30474558 | 0.76 | CHRM2 (0.46) | LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272835-A1 | NOVEL FIVE-MEMBERED RING COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-01-12 | — | — | EP | disclosed |