SCHEMBL1070722

SCHEMBL1070722

O=[C]c1ccc(C(=O)C(=O)c2cccc([C]=O)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CES2 O00748 17/20 0.46
CES1 P23141 15/20 0.46
GSK3B P49841 2/20 0.39
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5664511 0.78 GSK3B (0.42) CES2CES1GSK3B
SCHEMBL536823 0.78 CA12 (0.54) RAB9A
SCHEMBL4190711 0.77 CES2 (0.58) CES2CES1RAB9A
SCHEMBL1070719 0.76 MAPT (0.35)
SCHEMBL7136929 0.76 PARP1 (0.55) GSK3B
SCHEMBL5389398 0.76 MEN1 (0.50) RAB9A
SCHEMBL1679846 0.76 GSK3B (0.41) CES2CES1GSK3B
SCHEMBL103415 0.76 ALDH1A1 (0.47) CES2CES1GSK3B
SCHEMBL7068314 0.76 GSK3B (0.41) CES2CES1GSK3B
SCHEMBL102642 0.76 GSK3B (0.41) CES2CES1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111295929-B Desiccant, organic thin film containing same, organic laminate film having organic thin film laminated thereon, and electronic device provided with same 柯尼卡美能达株式会社 2023-08-08 CN disclosed
US-20230026150-A1 POLYETHER KETONE KETONE AND A PROCESS FOR PREPARATION THEREOF GHARDA CHEMICALS LIMITED (IN) 2023-01-26 US disclosed
WO-2021105784-A1 POLYETHER KETONE KETONE AND A PROCESS FOR PREPARATION THEREOF GHARDA CHEMICALS LIMITED (IN) 2021-06-03 WO disclosed
EP-2451858-B1 METHOD FOR PREPARING POLY (ETHER KETONE KETONES) KETONEX LTD (GB) 2020-10-28 EP disclosed
EP-3215564-B1 PROCESSES FOR INCREASING DENSITY OF POLYMER FLAKES AND POWDERS ARKEMA INC (US) 2020-09-30 EP disclosed
US-10450408-B2 Method for making polyarylaliphaticetherketone polymers and copolymers thereof KETONEX LIMITED (GB) 2019-10-22 US disclosed
US-10377846-B2 Processes for increasing density of polymer flakes and powders ARKEMA INC. (US) 2019-08-13 US disclosed
US-20170306075-A1 PROCESSES FOR INCREASING DENSITY OF POLYMER FLAKES AND POWDERS ARKEMA INC. 2017-10-26 US disclosed
EP-3215564-A2 PROCESSES FOR INCREASING DENSITY OF POLYMER FLAKES AND POWDERS Arkema, Inc. (US) 2017-09-13 EP disclosed
US-20170253696-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF OXFORD PERFORMANCE MATERIALS, INC 2017-09-07 US disclosed
EP-3191442-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF Ketonex Limited (GB) 2017-07-19 EP disclosed
WO-2016038370-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF KETONEX LIMITED (GB) 2016-03-17 WO disclosed
US-9023468-B2 Method for preparing poly (ether ketone ketones) KETONEX LIMITED (GB) 2015-05-05 US disclosed
US-20120263953-A1 METHOD FOR PREPARING POLY (ETHER KETONE KETONES) KETONEX LIMITED (GB) 2012-10-18 US disclosed
EP-2451858-A2 METHOD FOR PREPARING POLY (ETHER KETONE KETONES) Ketonex Limited (GB) 2012-05-16 EP disclosed
WO-2011004164-A2 METHOD FOR PREPARING POLY (ETHER KETONE KETONES) KETONEX LIMITED (GB) 2011-01-13 WO disclosed
EP-1179028-A1 SOLVENT RESISTANT PHOTOSENSITIVE COMPOSITIONS Syntrix Biochip, Inc. (US) 2002-02-13 EP disclosed
WO-2000032678-A1 SOLVENT RESISTANT PHOTOSENSITIVE COMPOSITIONS SYNTRIX BIOCHIP, INC. (US) 2000-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10450408-B2 Method for making polyarylaliphaticetherketone polymers and copolymers thereof DAO, DCXR, LOX CES2 2021/4885CES1 1426/4885GSK3B 2125/4885
US-20170253696-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF COASY, FRK, PBK CES2 1551/4885CES1 1618/4885GSK3B 1109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.