Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | DNTT | P04053 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707437 | 1.00 | HDAC3 (0.38) | HDAC3DNTTELANETRPA1NR4A2 | |
| SCHEMBL11234415 | 0.77 | HSD17B2 (0.35) | HDAC3ELANEHDAC4HDAC1HDAC7 | |
| SCHEMBL11234417 | 0.77 | HSD17B2 (0.35) | HDAC3ELANEHDAC4HDAC1HDAC7 | |
| SCHEMBL9546137 | 0.73 | L3MBTL1 (0.31) | ELANEMAPTLMNAALDH1A1HPGD | |
| SCHEMBL9546139 | 0.73 | L3MBTL1 (0.31) | ELANEMAPTLMNAALDH1A1HPGD | |
| SCHEMBL10619340 | 0.73 | DNTT (0.43) | DNTTTRPA1NR4A2MAPTUCHL3 | |
| SCHEMBL301113 | 0.65 | TRPA1 (0.47) | HDAC3TRPA1MAPTEGFRLMNA | |
| SCHEMBL160811 | 0.65 | TRPA1 (0.47) | HDAC3TRPA1MAPTEGFRLMNA | |
| SCHEMBL8722881 | 0.64 | EGFR (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5858046 | 0.64 | EGFR (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106576-B1 | NOVEL 5-MEMBERED CYCLIC COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |