Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546137 | 1.00 | L3MBTL1 (0.31) | L3MBTL1MEN1MAPTKMT2AHKDC1 | |
| SCHEMBL10707440 | 0.73 | HDAC3 (0.38) | MEN1MAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL10707437 | 0.73 | HDAC3 (0.38) | MEN1MAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL9546351 | 0.69 | ALDH1A1 (0.35) | L3MBTL1MEN1MAPTKMT2AHKDC1 | |
| SCHEMBL9546347 | 0.69 | ALDH1A1 (0.35) | L3MBTL1MEN1MAPTKMT2AHKDC1 | |
| SCHEMBL11234415 | 0.68 | HSD17B2 (0.35) | LMNAELANE | |
| SCHEMBL11234417 | 0.68 | HSD17B2 (0.35) | LMNAELANE | |
| SCHEMBL301113 | 0.57 | TRPA1 (0.47) | MAPTTDP1ALDH1A1LMNA | |
| SCHEMBL6547644 | 0.57 | MEN1 (0.43) | MEN1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL160811 | 0.57 | TRPA1 (0.47) | MAPTTDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |