Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15995119 | 0.94 | OPRM1 (0.42) | OPRM1PARP1HTR2AOPRK1OPRL1 | |
| SCHEMBL15995122 | 0.94 | OPRM1 (0.42) | OPRM1PARP1HTR2AOPRK1OPRL1 | |
| SCHEMBL21312268 | 0.94 | OPRM1 (0.42) | OPRM1PARP1HTR2AOPRK1OPRL1 | |
| SCHEMBL28483016 | 0.81 | OPRM1 (0.38) | OPRM1DPP4HTR2AAKR1C1SLC6A4 | |
| SCHEMBL19482450 | 0.81 | PARP1 (0.35) | PARP1 | |
| SCHEMBL19482449 | 0.81 | PARP1 (0.35) | PARP1 | |
| SCHEMBL11285777 | 0.79 | CHRNB2 (0.40) | OPRM1PARP1OPRL1 | |
| SCHEMBL9407936 | 0.77 | OPRM1 (0.41) | OPRM1DPP4HTR2AAKR1C1SLC6A4 | |
| SCHEMBL27306600 | 0.75 | OPRM1 (0.43) | OPRM1DPP4HTR2AAKR1C1SLC6A4 | |
| SCHEMBL24414771 | 0.74 | SLC6A3 (0.39) | PARP1SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |