Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 2/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HBB | P68871 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708407 | 1.00 | MAPT (0.64) | MAPTTDP1KMT2APOLBATM | |
| SCHEMBL11275822 | 0.87 | MAPT (0.55) | MAPTTDP1KMT2APOLBATM | |
| SCHEMBL30365137 | 0.82 | MAPT (0.54) | MAPTTDP1KMT2APOLBATM | |
| SCHEMBL30685494 | 0.80 | MAPT (0.60) | MAPTTDP1KMT2APOLBATM | |
| SCHEMBL28548773 | 0.80 | CYP1A2 (0.52) | MAPTTDP1KMT2APOLBATM | |
| SCHEMBL9659168 | 0.79 | MAPT (0.55) | MAPTTDP1KMT2APOLBATM | |
| SCHEMBL9659161 | 0.79 | MAPT (0.55) | MAPTTDP1KMT2APOLBATM | |
| SCHEMBL15014076 | 0.78 | KMT2A (1.00) | MAPTTDP1KMT2APOLBATM | |
| SCHEMBL5311972 | 0.77 | MAPT (0.49) | MAPTTDP1KMT2APOLBATM | |
| SCHEMBL5311974 | 0.77 | MAPT (0.49) | MAPTTDP1KMT2APOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115324-B1 | PROCESS FOR THE PREPARATION OF 2,4,5,6-TETRAAMINOPYRIMIDINE-SULPHATE | LONZA AG (CH) | 1988-10-26 | — | — | EP | claimed |
| EP-0115324-A2 | Process for the preparation of 2,4,5,6-tetraaminopyrimidine-sulphate | LONZA AG (CH) | 1984-08-08 | — | — | EP | claimed |
| EP-0115324-B1 | PROCESS FOR THE PREPARATION OF 2,4,5,6-TETRAAMINOPYRIMIDINE-SULPHATE | LONZA AG (CH) | 1988-10-26 | — | — | EP | disclosed |
| EP-0115324-A2 | Process for the preparation of 2,4,5,6-tetraaminopyrimidine-sulphate | LONZA AG (CH) | 1984-08-08 | — | — | EP | disclosed |
| EP-0115324-A2 | Process for the preparation of 2,4,5,6-tetraaminopyrimidine-sulphate | LONZA AG (CH) | 1984-08-08 | — | — | EP | disclosed |