SCHEMBL10708762

SCHEMBL10708762

CS(=O)(=O)OC1Oc2ccccc2C1=O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NT5E P21589 5/20 0.39
RET P07949 1/20 0.38
KDR P35968 1/20 0.38
STK17B O94768 1/20 0.36
CYP19A1 P11511 6/20 0.36
MAOB P27338 3/20 0.36
KDM4E B2RXH2 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
AR P10275 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4334851 0.79 NT5E (0.45) NT5ERETKDRSTK17BCYP19A1
SCHEMBL67633 0.73 POLB (0.46) RETKDRSTK17BCYP19A1MAOB
SCHEMBL5457239 0.72 RET (0.40) RETKDRSTK17BCYP19A1MAOB
SCHEMBL7534480 0.72 MEN1 (0.43) NT5ERETKDRSTK17BCYP19A1
SCHEMBL7539076 0.69 ALDH1A1 (0.49) KDM4EHSD17B10MAPT
SCHEMBL69430 0.69 PARP1 (0.48) RETKDRSTK17BCYP19A1MAOB
SCHEMBL10580552 0.67 STK17B (0.42) NT5ERETKDRSTK17BCYP19A1
SCHEMBL5548145 0.66 RET (0.46) RETKDRSTK17BCYP19A1MAOB
SCHEMBL92288 0.66 ESR1 (0.45) RETKDRSTK17BCYP19A1MAOB
SCHEMBL9434848 0.66 ESR1 (0.45) RETKDRSTK17BCYP19A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251465-A2 Light activatable anaerobic composition containing latent sulfonic acid source LOCTITE CORPORATION (US) 1988-01-07 EP claimed
EP-0251465-A2 Light activatable anaerobic composition containing latent sulfonic acid source LOCTITE CORPORATION (US) 1988-01-07 EP disclosed
EP-0249365-A2 Photocatalysts for vinyl compounds activated by an electron donating hetero atom LOCTITE (IRELAND) Ltd. (IE) 1987-12-16 EP disclosed
US-4708926-A SULFONIC ESTERS OF A-HYDROXYCARBONYL COMPOUNDS CIBA-GEIGY CORPORATION (US) 1987-11-24 US disclosed
US-4636575-A Masked curing catalyst for acid-curable compositions CIBA-GEIGY CORPORATION (US) 1987-01-13 US disclosed
US-4510290-A LATENCY; LOW-TEMPERATURE CURING BY SHORTWAVE RADIATION; INKS, LACQUERS CIBA GEIGY CORPORATION (US) 1985-04-09 US disclosed