SCHEMBL92288

SCHEMBL92288

CC1Oc2ccccc2C(=O)C1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
RET P07949 1/20 0.42
KDR P35968 1/20 0.42
CYP19A1 P11511 4/20 0.41
MAOB P27338 3/20 0.41
ADORA3 P0DMS8 2/20 0.41
KDM4E B2RXH2 2/20 0.41
AR P10275 1/20 0.41
HSD17B10 Q99714 1/20 0.41
STK17B O94768 1/20 0.41
POLB P06746 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPC1 O15118 2/20 0.39
MAPT P10636 2/20 0.39
MAPK1 P28482 2/20 0.39
RAB9A P51151 2/20 0.39
CYP3A4 P08684 1/20 0.39
PARP1 P09874 2/20 0.38
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8702376 1.00 ESR1 (0.45) ESR1RETKDRCYP19A1MAOB
SCHEMBL9434848 1.00 ESR1 (0.45) ESR1RETKDRCYP19A1MAOB
SCHEMBL27890291 0.81 RET (0.41) RETKDRCYP19A1MAOBADORA3
SCHEMBL87208 0.81 RET (0.41) ESR1RETKDRCYP19A1MAOB
SCHEMBL31015940 0.81 RET (0.41) ESR1RETKDRCYP19A1MAOB
SCHEMBL67624 0.81 RET (0.41) RETKDRCYP19A1MAOBADORA3
SCHEMBL5579742 0.79 ESR1 (0.56) ESR1RETKDRCYP19A1MAOB
SCHEMBL11043870 0.79 ESR1 (0.56) ESR1RETKDRCYP19A1MAOB
SCHEMBL69430 0.79 PARP1 (0.48) RETKDRCYP19A1MAOBADORA3
SCHEMBL15188492 0.78 MAOB (0.39) RETKDRCYP19A1MAOBADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10012902-B2 Positive resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-07-03 US disclosed
US-10012903-B2 Resist composition and pattern forming process SHIN-ESTU CHEMICAL CO., LTD. (JP) 2018-07-03 US disclosed
US-10005868-B2 Resist composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-26 US disclosed
US-10007178-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-26 US disclosed
US-20180024435-A1 RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-25 US disclosed
US-20180004087-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-04 US disclosed
US-9829792-B2 Monomer, polymer, positive resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-11-28 US disclosed
US-9810983-B2 Polymer, chemically amplified positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-11-07 US disclosed
US-20170277037-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-28 US disclosed
US-20170242339-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-24 US disclosed
US-20100227273-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-09-09 US disclosed
US-20100227274-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-09-09 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20090202940-A1 Positive resist composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-13 US disclosed
US-20090202947-A1 Positive resist composition and patterning process using the same SHIN-ETSU CHEMICAL CO.,LTD (JP) 2009-08-13 US disclosed
US-5723631-A Coumarin derivatives as retroviral inhibitors SMITHKLINE BEECHAM CORPORATION (US) 1998-03-03 US disclosed
EP-0674643-A1 COUMARIN DERIVATIVES AS RETROVIRAL INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1995-10-04 EP disclosed
EP-0674643-A4 COUMARIN DERIVATIVES AS RETROVIRAL INHIBITORS. SMITHKLINE BEECHAM CORP (US) 1995-08-08 EP disclosed
WO-1994014789-A1 COUMARIN DERIVATIVES AS RETROVIRAL INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1994-07-07 WO disclosed
EP-0277384-A2 1H-imidazole-5-carboxylic acid derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1988-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same PRRC2A, PUF60, POLR2B ESR1 1290/4885RET 2680/4885KDR 3040/4885
US-10012902-B2 Positive resist composition and pattern forming process EWSR1, SRPRA, SRPRB ESR1 510/4885RET 1089/4885KDR 2069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.