SCHEMBL69430

SCHEMBL69430

CC1Oc2ccccc2C1=O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.48
RET P07949 1/20 0.45
KDR P35968 1/20 0.45
CYP19A1 P11511 6/20 0.43
MAOB P27338 3/20 0.43
KDM4E B2RXH2 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
AR P10275 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
STK17B O94768 1/20 0.42
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28591473 0.88 PARP1 (0.46) PARP1RETKDRCYP19A1MAOB
SCHEMBL8702376 0.79 ESR1 (0.45) PARP1RETKDRCYP19A1MAOB
SCHEMBL92288 0.79 ESR1 (0.45) PARP1RETKDRCYP19A1MAOB
SCHEMBL9434848 0.79 ESR1 (0.45) PARP1RETKDRCYP19A1MAOB
SCHEMBL67624 0.76 RET (0.41) PARP1RETKDRCYP19A1MAOB
SCHEMBL31015940 0.76 RET (0.41) PARP1RETKDRCYP19A1MAOB
SCHEMBL87208 0.76 RET (0.41) PARP1RETKDRCYP19A1MAOB
SCHEMBL5548145 0.76 RET (0.46) PARP1RETKDRCYP19A1MAOB
SCHEMBL13928848 0.75 ALDH1A1 (0.46) RETKDRCYP19A1MAOBKDM4E
SCHEMBL11043870 0.75 ESR1 (0.56) RETKDRCYP19A1MAOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494985-B1 PRODUCTION AND PURIFICATION OF PHENOL: HYDROXYACETONE REMOVAL BY HYDROTALCITE SABIC INNOVATIVE PLASTICS IP (NL) 2014-04-23 EP claimed
EP-0372685-B1 Process for recovering phenol ENICHEM SPA (IT) 1995-06-14 EP claimed
US-20230348441-A1 BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR MEDSHINE DISCOVERY INC. (CN) 2023-11-02 US disclosed
US-20230348441-A1 BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR MEDSHINE DISCOVERY INC. (CN) 2023-11-02 US disclosed
US-20170266167-A1 ERK INHIBITORS MERCK SHARP & DOHME CORP. (US) 2017-09-21 US disclosed
EP-2053095-B2 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2017-02-22 EP disclosed
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
EP-2244984-B1 REMOVAL OF HYDROCARBONS FROM AN AQUEOUS STREAM BOREALIS TECH OY (FI) 2015-03-11 EP disclosed
US-8758573-B2 Removal of hydrocarbons from an aqueous stream BOREALIS TECHNOLOGY OY (FI) 2014-06-24 US disclosed
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080239045-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080239045-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
EP-1021431-A1 METHOD FOR PREPARING OPTIONALLY SUBSTITUTED BENZOFURANONES BAYER AG (DE) 2000-07-26 EP disclosed
WO-1999019316-A1 METHOD FOR PREPARING OPTIONALLY SUBSTITUTED BENZOFURANONES BAYER AKTIENGESELLSCHAFT (DE) 1999-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348441-A1 BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR CRBN, CRKL, NCOR1 PARP1 4625/4885RET 43/4885KDR 493/4885
US-20170266167-A1 ERK INHIBITORS MAPK1, MAPK3, MAPK6 PARP1 2450/4885RET 262/4885KDR 782/4885
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 PARP1 2522/4885RET 755/4885KDR 2861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.