Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.43 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.43 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.43 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670150 | 0.91 | MEN1 (0.50) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL31053826 | 0.84 | L3MBTL1 (0.56) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL1792324 | 0.84 | L3MBTL1 (0.56) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL20739827 | 0.83 | POLM (0.62) | KMT2AMEN1KDM4ERECQLPOLM | |
| SCHEMBL26090058 | 0.83 | POLM (0.62) | KMT2AMEN1KDM4ERECQLPOLM | |
| SCHEMBL3361882 | 0.82 | KMT2A (0.59) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL4085609 | 0.81 | MEN1 (0.67) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL16800404 | 0.80 | KDM4E (0.66) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL4090350 | 0.80 | MEN1 (0.60) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL4961740 | 0.80 | AKT1 (0.45) | KMT2AMAPTMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266979-A2 | Therapeutic agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-11 | — | — | EP | disclosed |