Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 12/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | PRCP | P42785 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23565690 | 0.97 | FKBP1A (0.64) | FKBP1AEPHX2PRCPSMN1; SMN2ALDH1A1 | |
| SCHEMBL11096695 | 0.94 | MEN1 (0.61) | FKBP1ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28628871 | 0.94 | MEN1 (0.61) | FKBP1ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28622807 | 0.88 | CYP3A4 (0.57) | FKBP1ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4366597 | 0.87 | ALDH1A1 (0.64) | FKBP1ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6508896 | 0.87 | ALDH1A1 (0.64) | FKBP1ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL5173012 | 0.87 | ALDH1A1 (0.64) | FKBP1ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL12972657 | 0.86 | ALDH1A1 (0.59) | FKBP1APRCPSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL18555855 | 0.86 | FKBP1A (0.71) | FKBP1AEPHX2PRCPMEN1KMT2A | |
| SCHEMBL31420576 | 0.85 | PRCP (0.58) | FKBP1APRCPSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767744-A | Substituted tyrosyl methionyl dipeptide amides | G. D. SEARLE & CO. (US) | 1988-08-30 | — | — | US | disclosed |
| US-4450155-A | DERIVATIVES OF TYROSINE-PROLINE POLYPEPTIDES | STERLING DRUG INC. (US) | 1984-05-22 | — | — | US | disclosed |