Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574458 | 0.70 | LMNA (0.35) | ALDH1A1MAPTUSP2NPSR1ALOX15 | |
| SCHEMBL141302 | 0.70 | F2 (0.63) | ALDH1A1HSD17B10MAPTHTTUSP2 | |
| Hydrochloric Acid SCHEMBL8590266 | 0.68 | F2 (0.60) | ALDH1A1HSD17B10MAPTHTTUSP2 | |
| SCHEMBL21996053 | 0.68 | F2 (0.60) | ALDH1A1HSD17B10MAPTHTTUSP2 | |
| SCHEMBL3831786 | 0.68 | F2 (0.60) | ALDH1A1HSD17B10MAPTHTTUSP2 | |
| SCHEMBL28653859 | 0.68 | MEN1 (0.44) | HSD17B10MAPTALOX15POLBRAB9A | |
| SCHEMBL5443739 | 0.68 | HPGD (0.46) | ALDH1A1HSD17B10MAPTHTTUSP2 | |
| SCHEMBL5440608 | 0.67 | MAPT (0.50) | ALDH1A1MAPTHTTF2ELANE | |
| Hydrochloric Acid SCHEMBL8763377 | 0.66 | F2 (0.57) | ALDH1A1HSD17B10MAPTHTTUSP2 | |
| Methylamine SCHEMBL11674255 | 0.66 | F2 (0.57) | ALDH1A1HSD17B10MAPTHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684728-A | Solubilizing biologically active compounds with reactive hydrogen atoms | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-04 | — | — | US | disclosed |