Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.39 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | CTSG | P08311 | 1/20 | 0.57 |
| ▸ | CTRC | Q99895 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8590266 | 0.97 | F2 (0.60) | F2ELANECTSGCTRCSMN1; SMN2 | |
| SCHEMBL3831786 | 0.97 | F2 (0.60) | F2ELANECTSGCTRCSMN1; SMN2 | |
| SCHEMBL141302 | 0.95 | F2 (0.63) | F2ELANECTSGCTRCSMN1; SMN2 | |
| SCHEMBL21996053 | 0.92 | F2 (0.60) | F2ELANECTSGCTRCSMN1; SMN2 | |
| Water SCHEMBL29185040 | 0.90 | F2 (0.57) | F2ELANECTSGCTRCSMN1; SMN2 | |
| Methylamine SCHEMBL11674255 | 0.90 | F2 (0.57) | F2ELANECTSGCTRCSMN1; SMN2 | |
| Potassium Ion SCHEMBL28557553 | 0.90 | F2 (0.57) | F2ELANECTSGCTRCSMN1; SMN2 | |
| Acetic Acid SCHEMBL6771125 | 0.84 | F2 (0.50) | F2ELANECTSGCTRCSMN1; SMN2 | |
| SCHEMBL14582192 | 0.84 | F2 (0.50) | F2ELANECTSGCTRCSMN1; SMN2 | |
| Phosphoric Acid SCHEMBL2463241 | 0.84 | F2 (0.50) | F2ELANECTSGCTRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600441-B1 | Laser marking and printing ink therefor | DAINIPPON INK & CHEMICALS (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0601444-B1 | Label printing apparatus | KIRIN BREWERY (JP) | 1996-08-28 | — | — | EP | disclosed |
| US-5528280-A | Label printing apparatus for laser printing a heat-sensitive color developing ink layer of the label | KIRIN BEER KABUSHIKI KAISHA (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5413629-A | Background color inhibitor | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1995-05-09 | — | — | US | disclosed |
| US-5384401-A | Aldehyde containing polymer reacted with amine chelating agent, attachment of radioactive label | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1995-01-24 | — | — | US | disclosed |
| EP-0601444-A1 | Label printing apparatus | KIRIN BEER KABUSHIKI KAISHA (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0600441-A1 | Laser marking and printing ink therefor | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-5077389-A | Polyformyl compound with amino-containing chelating and physiologically active compounds bonded thereto via methyleneimine or methyleneamine linkages | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0111311-B1 | NON-RADIOACTIVE CARRIERS AND RADIOACTIVE DIAGNOSTIC AGENT | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4469780-A | COMBINED DEVELOPMENT AND INTENSIFICATION BATH | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-04 | — | — | US | disclosed |
| EP-0111311-A2 | Non-radioactive carriers and radioactive diagnostic agent | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1984-06-20 | — | — | EP | disclosed |