Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22606188 | 0.80 | MGLL (0.36) | LMNAMAPTKMT2AHDAC4HDAC2 | |
| SCHEMBL24235960 | 0.78 | LMNA (0.37) | LMNAMAPTKMT2AHDAC4HDAC2 | |
| SCHEMBL28653859 | 0.75 | MEN1 (0.44) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL10457256 | 0.74 | MAPT (0.43) | LMNAMAPTKMT2AHDAC4HDAC2 | |
| SCHEMBL3053165 | 0.74 | MEN1 (0.46) | LMNAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL29114362 | 0.73 | LMNA (0.39) | LMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL7646639 | 0.72 | ALDH1A1 (0.41) | LMNAKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL6192527 | 0.72 | ALDH1A1 (0.37) | LMNAMAPTKMT2AMEN1USP2 | |
| SCHEMBL1159966 | 0.71 | LMNA (0.34) | LMNAKMT2ACA12CA1CA9 | |
| SCHEMBL10709207 | 0.70 | ALDH1A1 (0.34) | MAPTUSP2NPSR1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018833-A1 | POLY(VINYL AMINE) ANALOGS | UNIVERSITY OF MASSACHUSETTS (US) | 1998-05-07 | — | — | WO | disclosed |