SCHEMBL10709362

SCHEMBL10709362

CCOC(=O)CCOC(C)N1C=NCC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
RAB9A P51151 1/20 0.33
NOTUM Q6P988 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
CHRM1 P11229 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
NR1I2 O75469 1/20 0.30
PGR P06401 1/20 0.30
ADORA3 P0DMS8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3823424 0.72 CYP1A2 (0.47) TSHRLMNAPOLBALDH1A1KMT2A
SCHEMBL10709355 0.71 LMNA (0.35) TSHRLMNAPOLBALDH1A1MEN1
SCHEMBL11609810 0.71 ALDH1A1 (0.40) TSHRLMNAPOLBALDH1A1L3MBTL1
SCHEMBL10709347 0.66 TSHR (0.31) TSHRLMNAALDH1A1KMT2ARAB9A
SCHEMBL31671147 0.65 CYP1A2 (0.40) TSHRLMNAPOLBALDH1A1KMT2A
SCHEMBL27512600 0.64 CYP3A4 (0.50) POLBALDH1A1MEN1KMT2ACYP4F2
SCHEMBL4409901 0.63 GAA (0.50) TSHRLMNAPOLBALDH1A1KMT2A
SCHEMBL25090508 0.63 LMNA (0.55) TSHRLMNAPOLBALDH1A1KMT2A
SCHEMBL11232153 0.63 HTT (0.32) TSHRALDH1A1
SCHEMBL27586492 0.63 KMT2A (0.44) TSHRLMNAALDH1A1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0275907-A2 Rim polyurethane or polyurea compositions containing internal mold release agents MOBAY CORPORATION (US) 1988-07-27 EP disclosed