SCHEMBL11232153

SCHEMBL11232153

CCOCCC(=O)ON1C=NCC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.32
NAMPT P43490 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29172177 0.84 ALDH1A1 (0.38) ALDH1A1
SCHEMBL1487752 0.80 ALDH1A1 (0.31) ALDH1A1
SCHEMBL29172172 0.79 NAAA (0.43) ALDH1A1TSHR
SCHEMBL28624648 0.79 NAAA (0.43) ALDH1A1TSHR
SCHEMBL28382148 0.79 NAAA (0.43) ALDH1A1TSHR
SCHEMBL8359052 0.78 EGLN1 (0.32) ALDH1A1
SCHEMBL29180057 0.76 MGLL (0.33)
SCHEMBL5933426 0.74
SCHEMBL29172200 0.73 GLA (0.33)
SCHEMBL28383204 0.72 ALDH1A1 (0.44) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4347154-A Methylene chloride stabilizer formulation for use in aerosols THE DOW CHEMICAL COMPANY (US) 1982-08-31 US disclosed