SCHEMBL10709482

SCHEMBL10709482

Cc1ccc(S(=O)(=O)OC(C)C(=O)c2ccc(Sc3ccccc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 7/20 0.45
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MAPT P10636 2/20 0.40
MMP1 P03956 2/20 0.40
MMP2 P08253 2/20 0.40
HKDC1 Q2TB90 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3096091 0.88 RECQL (0.49) ALDH1A1NPC1GAANFKB1RAB9A
SCHEMBL3089042 0.86 KMT2A (0.49) ALDH1A1HPGDNPC1GAANFKB1
SCHEMBL3095908 0.85 ALDH1A1 (0.44) ALDH1A1NPC1GAANFKB1RAB9A
SCHEMBL10710266 0.81 ALDH1A1 (0.46) MMP13ALDH1A1GAASMN1; SMN2KMT2A
SCHEMBL10709364 0.79 KMT2A (0.48) ALDH1A1HPGDNPC1RAB9AKMT2A
SCHEMBL10811773 0.79 TDP1 (0.56) ALDH1A1HPGDNPC1GAARAB9A
SCHEMBL10807674 0.78 RECQL (0.50) ALDH1A1NPC1GAARAB9ASMN1; SMN2
Butane SCHEMBL10879736 0.77 RECQL (0.42) ALDH1A1HPGDNPC1GAANFKB1
SCHEMBL3084336 0.76 RECQL (0.46) MMP13ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL4372757 0.76 MMP9 (0.45) MMP13ALDH1A1GAASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251465-A2 Light activatable anaerobic composition containing latent sulfonic acid source LOCTITE CORPORATION (US) 1988-01-07 EP claimed
EP-0251465-A2 Light activatable anaerobic composition containing latent sulfonic acid source LOCTITE CORPORATION (US) 1988-01-07 EP disclosed
US-4708926-A SULFONIC ESTERS OF A-HYDROXYCARBONYL COMPOUNDS CIBA-GEIGY CORPORATION (US) 1987-11-24 US disclosed
US-4636575-A Masked curing catalyst for acid-curable compositions CIBA-GEIGY CORPORATION (US) 1987-01-13 US disclosed
US-4510290-A LATENCY; LOW-TEMPERATURE CURING BY SHORTWAVE RADIATION; INKS, LACQUERS CIBA GEIGY CORPORATION (US) 1985-04-09 US disclosed