Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269128 | 0.81 | KCNN4 (0.38) | SIGMAR1TP53LMNAGAAMAPT | |
| SCHEMBL2103327 | 0.74 | HTT (0.33) | SIGMAR1TP53HTTGAAMAPT | |
| SCHEMBL2101823 | 0.72 | KCNH2 (0.37) | SIGMAR1GAAMAPTNPSR1 | |
| SCHEMBL10710891 | 0.70 | SIGMAR1 (0.44) | SIGMAR1KMT2ATP53LMNAL3MBTL1 | |
| SCHEMBL2103221 | 0.69 | PGR (0.35) | KMT2AMAPT | |
| SCHEMBL2100308 | 0.68 | TAAR1 (0.35) | SIGMAR1MAPTALOX12TAAR1 | |
| SCHEMBL2269741 | 0.67 | — | — | |
| SCHEMBL2101906 | 0.67 | MAPT (0.33) | MAPT | |
| SCHEMBL6114070 | 0.67 | HPGD (0.37) | LMNAHTTGAAMAPT | |
| SCHEMBL11496456 | 0.66 | HTR1B (0.35) | KMT2ALMNAHTTL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233990-B2 | Organoaminosilanes and methods for making same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| EP-0112434-B1 | HYDROGEN BEARING SILYL CARBAMATES | UNION CARBIDE CORPORATION (US) | 1988-08-17 | — | — | EP | disclosed |