Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709796 | 1.00 | FOLH1 (0.42) | FOLH1ACECPB2MMP2MMP9 | |
| SCHEMBL364063 | 0.79 | CPB2 (0.50) | FOLH1ACECPB2MMP2MMP9 | |
| SCHEMBL364062 | 0.79 | CPB2 (0.50) | FOLH1ACECPB2MMP2MMP9 | |
| SCHEMBL8934904 | 0.72 | KMT2A (0.40) | FOLH1MMP2MMP9CA1CA2 | |
| SCHEMBL30332077 | 0.72 | FOLH1 (0.45) | FOLH1ACECPB2MMP2MMP9 | |
| SCHEMBL8934927 | 0.72 | KMT2A (0.40) | FOLH1MMP2MMP9CA1CA2 | |
| SCHEMBL8934926 | 0.71 | FOLH1 (0.46) | FOLH1MMP9 | |
| SCHEMBL8934928 | 0.71 | FOLH1 (0.46) | FOLH1MMP9 | |
| SCHEMBL23501516 | 0.70 | FOLH1 (0.39) | FOLH1ACECPB2MMP2MMP9 | |
| SCHEMBL34475333 | 0.70 | FOLH1 (0.44) | FOLH1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097031-B1 | NONAPEPTIDE AND DECAPEPTIDE ANALOGS OF LHRH USEFUL AS LHRH ANTAGONISTS, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1988-09-21 | — | — | EP | disclosed |
| EP-0097031-A2 | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists, their preparation and compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1983-12-28 | — | — | EP | disclosed |