Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.46 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.46 |
| ▸ | GGH | Q92820 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934926 | 1.00 | FOLH1 (0.46) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL34475333 | 0.98 | FOLH1 (0.44) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL8934927 | 0.87 | KMT2A (0.40) | FOLH1NAALAD2RIMKLAMMP9 | |
| SCHEMBL8934904 | 0.87 | KMT2A (0.40) | FOLH1NAALAD2RIMKLAMMP9 | |
| SCHEMBL11143392 | 0.84 | FOLH1 (0.50) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL30118318 | 0.81 | TGFBR1 (0.36) | — | |
| SCHEMBL10378031 | 0.73 | ITGB3 (0.34) | — | |
| SCHEMBL4529797 | 0.73 | POLB (0.49) | NAALAD2MMP9 | |
| SCHEMBL5282039 | 0.72 | CA2 (0.40) | FOLH1NAALAD2RIMKLAGAASMN1; SMN2 | |
| SCHEMBL5282044 | 0.72 | CA2 (0.40) | FOLH1NAALAD2RIMKLAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029088-A1 | NOVEL PIPERAZINE DERIVATIVES AS TYPE IL-1 RECEPTOR ANTAGONISTS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-09-26 | — | — | WO | disclosed |