Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934904 | 1.00 | KMT2A (0.40) | KMT2AMMP2MMP9CA2CA1 | |
| SCHEMBL8934928 | 0.87 | FOLH1 (0.46) | MMP9FOLH1RIMKLANAALAD2 | |
| SCHEMBL8934926 | 0.87 | FOLH1 (0.46) | MMP9FOLH1RIMKLANAALAD2 | |
| SCHEMBL34475333 | 0.86 | FOLH1 (0.44) | MMP9FOLH1RIMKLANAALAD2 | |
| SCHEMBL28307549 | 0.84 | L3MBTL1 (0.42) | KMT2AMMP2MMP9CA2CA1 | |
| SCHEMBL30118318 | 0.78 | TGFBR1 (0.36) | CA2CA1GNAI3GNAO1GNAI1 | |
| SCHEMBL10709791 | 0.72 | FOLH1 (0.42) | MMP2MMP9CA2CA1FOLH1 | |
| SCHEMBL11143392 | 0.71 | FOLH1 (0.50) | MMP9FOLH1RIMKLANAALAD2 | |
| SCHEMBL4529797 | 0.71 | POLB (0.49) | KMT2AMMP2MMP9L3MBTL1ITGB3 | |
| SCHEMBL24213220 | 0.70 | KMT2A (0.50) | KMT2AMMP2MMP9CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029088-A1 | NOVEL PIPERAZINE DERIVATIVES AS TYPE IL-1 RECEPTOR ANTAGONISTS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-09-26 | — | — | WO | disclosed |