Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422421 | 1.00 | REN (0.43) | REN | |
| SCHEMBL10422420 | 0.83 | REN (0.49) | REN | |
| SCHEMBL10710118 | 0.83 | REN (0.49) | REN | |
| SCHEMBL10710121 | 0.82 | REN (0.45) | REN | |
| SCHEMBL10421152 | 0.80 | APP (0.36) | REN | |
| SCHEMBL10421176 | 0.77 | REN (0.47) | REN | |
| SCHEMBL10422719 | 0.77 | REN (0.47) | REN | |
| SCHEMBL10707389 | 0.75 | REN (0.41) | REN | |
| SCHEMBL10421236 | 0.75 | REN (0.41) | REN | |
| SCHEMBL7375834 | 0.73 | REN (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281316-A2 | Renin inhibitors | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |