Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844532 | 0.78 | REN (0.46) | RENCTSS | |
| SCHEMBL7316055 | 0.74 | REN (0.42) | RENCTSS | |
| SCHEMBL7317681 | 0.74 | REN (0.42) | RENCTSS | |
| SCHEMBL10422421 | 0.73 | REN (0.43) | REN | |
| SCHEMBL10710119 | 0.73 | REN (0.43) | REN | |
| SCHEMBL10422719 | 0.73 | REN (0.47) | REN | |
| SCHEMBL10421176 | 0.73 | REN (0.47) | REN | |
| SCHEMBL9575192 | 0.72 | REN (0.39) | RENCTSS | |
| SCHEMBL7275460 | 0.72 | REN (0.60) | REN | |
| SCHEMBL7275457 | 0.72 | REN (0.60) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314239-A2 | Tripeptide renin inhibitors with N-terminal ureido or sulfamido groups | MERCK & CO. INC. (US) | 1989-05-03 | — | — | EP | disclosed |