SCHEMBL10710121

SCHEMBL10710121

CCCCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N(C(=O)[C@@H](N)Cc1cnc[nH]1)C(CC1CCCCC1)C(O)CSc1nccs1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10422421 0.82 REN (0.43) REN
SCHEMBL10710119 0.82 REN (0.43) REN
SCHEMBL10710118 0.76 REN (0.49) REN
SCHEMBL10422420 0.76 REN (0.49) REN
SCHEMBL10707393 0.74 REN (0.49) REN
SCHEMBL10421241 0.70 REN (0.57) REN
SCHEMBL7319700 0.68 REN (0.41) REN
SCHEMBL7319704 0.68 REN (0.41) REN
SCHEMBL7313206 0.64 REN (0.48) REN
SCHEMBL10421152 0.63 APP (0.36) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281316-A2 Renin inhibitors YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-09-07 — — EP disclosed
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