Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 10/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713239 | 0.87 | TDP2 (0.41) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL10711958 | 0.77 | TDP2 (0.55) | CYP19A1CYP11B1CYP11B2TDP2GRIA1 | |
| SCHEMBL10710535 | 0.76 | AHR (0.53) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL10714770 | 0.76 | GRIA1 (0.65) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL154730 | 0.74 | AHR (0.41) | CYP19A1CYP11B1CYP11B2TDP2CASP3 | |
| SCHEMBL5373768 | 0.73 | TDP2 (0.49) | CYP19A1CYP11B1CYP11B2TDP2CASP3 | |
| SCHEMBL837443 | 0.73 | AHR (0.61) | CYP19A1CYP11B1CYP11B2TDP2CASP3 | |
| SCHEMBL10714240 | 0.71 | TDP2 (0.49) | CYP19A1CYP11B1CYP11B2TDP2CASP3 | |
| SCHEMBL4410702 | 0.70 | AHR (0.49) | CYP19A1CYP11B1CYP11B2TDP2GRIA1 | |
| SCHEMBL18210439 | 0.70 | AHR (0.41) | CYP19A1CYP11B1CYP11B2TDP2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |