Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 9/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10712267 | 0.84 | TDP2 (0.58) | TDP2GRIA1CACNG8AHRPDE3B | |
| SCHEMBL10714905 | 0.79 | TDP2 (0.52) | TDP2GRIA1CACNG8AHRCMA1 | |
| SCHEMBL10711238 | 0.77 | CYP19A1 (0.45) | TDP2CYP19A1CYP11B1CYP11B2GRIA1 | |
| SCHEMBL10713895 | 0.76 | ALDH1A1 (0.50) | TDP2GRIA1CACNG8PDE3BPDE3A | |
| SCHEMBL5373768 | 0.74 | TDP2 (0.49) | TDP2CYP19A1CYP11B1CYP11B2AHR | |
| SCHEMBL10711906 | 0.73 | PDE3B (0.68) | TDP2CYP11B1CYP11B2GRIA1CACNG8 | |
| SCHEMBL10711419 | 0.73 | TDP2 (0.52) | TDP2GRIA1CACNG8AHRCMA1 | |
| SCHEMBL154730 | 0.71 | AHR (0.41) | TDP2CYP19A1CYP11B1CYP11B2GRIA1 | |
| SCHEMBL4410702 | 0.71 | AHR (0.49) | TDP2CYP19A1CYP11B1CYP11B2GRIA1 | |
| SCHEMBL18210439 | 0.71 | AHR (0.41) | TDP2CYP19A1CYP11B1CYP11B2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |