Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | GABRE | P78334 | 3/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713526 | 0.88 | GABRP (0.42) | TSHRCASP1GABRPGABRDGABRA1 | |
| Cyclohexanone Oxime SCHEMBL27858767 | 0.80 | TSHR (0.56) | TSHRCASP1GABRPGABRDGABRA1 | |
| SCHEMBL10712733 | 0.78 | — | — | |
| SCHEMBL11792080 | 0.78 | SMN1; SMN2 (0.39) | TSHRCASP1SMN1; SMN2POLBTP53 | |
| SCHEMBL11260907 | 0.74 | GABRP (0.45) | TSHRCASP1GABRPGABRDGABRA1 | |
| SCHEMBL15043867 | 0.72 | THRB (0.42) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL535720 | 0.72 | THRB (0.42) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3934728 | 0.72 | THRB (0.42) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL16731182 | 0.71 | SLC6A1 (0.38) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22100988 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129947-B1 | CONTRACEPTIVE COMPOSITIONS BASED ON ESTERS OF LEVO-NORGESTREL | WORLD HEALTH ORGANISATION (CH) | 1988-09-14 | — | — | EP | claimed |
| EP-0129947-A2 | Contraceptive compositions based on esters of levo-norgestrel | WORLD HEALTH ORGANISATION (CH) | 1985-01-02 | — | — | EP | claimed |
| EP-0129947-B1 | CONTRACEPTIVE COMPOSITIONS BASED ON ESTERS OF LEVO-NORGESTREL | WORLD HEALTH ORGANISATION (CH) | 1988-09-14 | — | — | EP | disclosed |
| EP-0129947-A2 | Contraceptive compositions based on esters of levo-norgestrel | WORLD HEALTH ORGANISATION (CH) | 1985-01-02 | — | — | EP | disclosed |
| EP-0129947-A2 | Contraceptive compositions based on esters of levo-norgestrel | WORLD HEALTH ORGANISATION (CH) | 1985-01-02 | — | — | EP | disclosed |
| US-3931288-A | ANTIINFLAMMATORY, ANTIRHEUMATIC | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |