Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711604 | 0.96 | REN (0.58) | RENMMP2MMP9MMP8 | |
| SCHEMBL10421155 | 0.92 | REN (0.59) | RENMMP2MMP9MMP8 | |
| SCHEMBL10422015 | 0.90 | REN (0.58) | RENMMP2MMP9MMP8 | |
| SCHEMBL10421234 | 0.90 | REN (0.56) | RENMMP2MMP9MMP8 | |
| SCHEMBL10421552 | 0.90 | REN (0.56) | REN | |
| SCHEMBL10420799 | 0.86 | REN (0.55) | REN | |
| SCHEMBL10750338 | 0.86 | REN (0.79) | RENMMP2MMP9MMP8 | |
| SCHEMBL10712236 | 0.84 | REN (0.42) | RENMMP2MMP9MMP8 | |
| SCHEMBL10756718 | 0.84 | REN (0.53) | RENMMP2MMP9MMP8 | |
| SCHEMBL7333736 | 0.84 | REN (0.53) | RENMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281316-A2 | Renin inhibitors | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |