Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711608 | 0.96 | REN (0.41) | RENSSTR4MMP2MMP9MMP8 | |
| SCHEMBL10708990 | 0.87 | REN (0.38) | RENSSTR4 | |
| SCHEMBL10708945 | 0.85 | REN (0.45) | REN | |
| SCHEMBL10712228 | 0.84 | REN (0.59) | RENMMP2MMP9MMP8 | |
| SCHEMBL10711604 | 0.81 | REN (0.58) | RENMMP2MMP9MMP8 | |
| SCHEMBL10422706 | 0.79 | REN (0.48) | REN | |
| SCHEMBL10709088 | 0.79 | REN (0.46) | REN | |
| SCHEMBL10421139 | 0.78 | REN (0.52) | REN | |
| SCHEMBL9740281 | 0.77 | REN (0.43) | REN | |
| SCHEMBL10421155 | 0.77 | REN (0.59) | RENMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281316-A2 | Renin inhibitors | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |