Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717505 | 0.86 | AKR1C2 (0.44) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL14764650 | 0.83 | GABRA1 (0.46) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10807353 | 0.82 | NR1I2 (0.38) | ALDH1A1KDM4ELMNASMN1; SMN2NR5A2 | |
| SCHEMBL10713139 | 0.79 | KDM4E (0.37) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11289049 | 0.79 | MEN1 (0.44) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL18646168 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10469464 | 0.78 | GABRA1 (0.41) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL11561649 | 0.77 | AKR1C2 (0.47) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL4075760 | 0.77 | NR5A2 (0.55) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10395320 | 0.75 | HIF1A (0.48) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135860-B1 | DERIVATIVES OF 6-SULFOXYPHENOL, THEIR PREPARATION AND THEIR USE AS CYTOPROTECTORS; USE OF DERIVATIVES OF SALICYLALDEHYDE AS CYTOPROTECTORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-02 | — | — | EP | disclosed |
| US-4661636-A | 6-sulfoxyphenol derivatives, their preparation and their use as cytoprotective agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-28 | — | — | US | disclosed |
| EP-0135860-A2 | Derivatives of 6-sulfoxyphenol, their preparation and their use as cytoprotectors; use of derivatives of salicylaldehyde as cytoprotectors | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-03 | — | — | EP | disclosed |