SCHEMBL14764650

SCHEMBL14764650

CC(=O)c1cc(C(C)(C)C)cc(C(C)=O)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
NSD2 O96028 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
MCL1 Q07820 1/20 0.42
NR5A2 O00482 1/20 0.41
NR5A1 Q13285 1/20 0.41
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
CYP2C19 P33261 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11561649 0.92 AKR1C2 (0.47) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL10469464 0.90 GABRA1 (0.41) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL4075760 0.88 NR5A2 (0.55) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL11289049 0.86 MEN1 (0.44) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL10395320 0.86 HIF1A (0.48) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL10712901 0.83 ALDH1A1 (0.36) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL6971420 0.83 GAA (0.47) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL28717119 0.82 AKR1C2 (0.53) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL11349479 0.82 CYP2C19 (0.42) GABRA1GABRB2MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL11340256 0.80 PLG (0.43) GABRA1GABRB2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3312214-B1 METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT IMPERIAL INNOVATIONS LTD (GB) 2023-08-16 EP disclosed
CN-108707225-B Method for synthesizing polycarbonate in presence of bimetallic catalyst and chain transfer agent IP2IPO创新有限公司 2021-07-02 CN disclosed
EP-3312214-A1 METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT Imperial Innovations Limited (GB) 2018-04-25 EP disclosed
EP-2753651-B1 METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT IMP INNOVATIONS LTD (GB) 2017-07-12 EP disclosed
US-9006347-B2 Method of synthesising polycarbonates in the presence of a bimetallic catalyst and a chain transfer agent IMPERIAL INNOVATIONS LIMITED (GB) 2015-04-14 US disclosed
US-20140249279-A1 METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT IMPERIAL INNOVATIONS LIMITED (GB) 2014-09-04 US disclosed
WO-2013034750-A9 METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT IMPERIAL INNOVATIONS LIMITED (GB) 2013-09-06 WO disclosed
WO-2013034750-A2 METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT IMPERIAL INNOVATIONS LIMITED (GB) 2013-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140249279-A1 METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT TECR, MCM4, PCCA GABRA1 2959/4885GABRB2 3419/4885MEN1 1217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.