Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701352 | 0.93 | FFAR4 (0.40) | TTRFFAR4DRD4HTR2ASLC6A4 | |
| SCHEMBL7922539 | 0.81 | TTR (0.44) | TTRFFAR4HTR2ASLC6A4LPAR1 | |
| SCHEMBL9558602 | 0.80 | FFAR4 (0.44) | FFAR4LPAR1LPAR5 | |
| SCHEMBL10740183 | 0.79 | TTR (0.47) | TTRFFAR4HTR2ASLC6A4LMNA | |
| SCHEMBL11141496 | 0.79 | TSHR (0.48) | TTRFFAR4LPAR1LPAR5 | |
| SCHEMBL10432985 | 0.77 | TTR (0.41) | TTRFFAR4HTR2ASLC6A4LPAR1 | |
| SCHEMBL10361908 | 0.76 | TTR (0.42) | TTRFFAR4HTR2ASLC6A4LPAR1 | |
| SCHEMBL10719715 | 0.76 | TTR (0.39) | TTRFFAR4LPAR1LPAR5 | |
| SCHEMBL9558218 | 0.76 | RIPK1 (0.41) | TTRFFAR4HTR2ASLC6A4LPAR1 | |
| SCHEMBL10361910 | 0.76 | TTR (0.40) | TTRFFAR4LPAR1LPAR5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268560-A2 | Substituted phenoxybenzyl-(dihalogen-dimethyl-cyclopropyl-methyl) ether | CIBA-GEIGY AG (CH) | 1988-05-25 | — | — | EP | disclosed |