SCHEMBL10714367

SCHEMBL10714367

O=c1oc(-c2ccccc2NS(=O)(=O)c2cccc3ccccc23)nc2ccccc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.74
MEN1 O00255 3/20 0.74
LMNA P02545 2/20 0.69
MAPT P10636 4/20 0.67
ALDH1A1 P00352 2/20 0.67
GAA P10253 2/20 0.67
C1R P00736 8/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
PRSS1 P07477 2/20 0.51
F2 P00734 2/20 0.51
PLG P00747 1/20 0.51
KLK1 P06870 1/20 0.51
C1S P09871 1/20 0.51
ATM Q13315 1/20 0.51
PTPN2 P17706 1/20 0.47
PTPN1 P18031 1/20 0.47
PTPN5 P54829 1/20 0.47
PGAM1 P18669 1/20 0.47
ELANE P08246 1/20 0.47
ACLY P53396 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5974887 0.87 KMT2A (0.73) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL20544625 0.86 KMT2A (0.67) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL5975597 0.85 KMT2A (1.00) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL10819490 0.82 KMT2A (0.88) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL2314299 0.82 KMT2A (1.00) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL30183217 0.82 KMT2A (1.00) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL7200936 0.82 KMT2A (0.75) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL9528544 0.81 KMT2A (0.86) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL5975754 0.81 KMT2A (0.84) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL924320 0.81 MAPT (1.00) KMT2AMEN1LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4707297-A Removable guidepath for automated guidance vehicles BELL & HOWELL COMPANY (US) 1987-11-17 US claimed
US-4707297-A Removable guidepath for automated guidance vehicles BELL & HOWELL COMPANY (US) 1987-11-17 US disclosed