SCHEMBL7200936

SCHEMBL7200936

CS(=O)(=O)Nc1ccccc1-c1nc2ccccc2c(=O)o1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.75
MEN1 O00255 3/20 0.75
MAPT P10636 4/20 0.67
ALDH1A1 P00352 3/20 0.67
GAA P10253 1/20 0.67
LMNA P02545 2/20 0.66
C1R P00736 8/20 0.57
F2 P00734 2/20 0.57
PLG P00747 1/20 0.57
KLK1 P06870 1/20 0.57
PRSS1 P07477 1/20 0.57
C1S P09871 1/20 0.57
ATM Q13315 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ELANE P08246 3/20 0.52
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
KLK3 P07288 1/20 0.50
KDM4E B2RXH2 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5975597 0.86 KMT2A (1.00) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL8364059 0.83 KMT2A (0.66) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL5974887 0.83 KMT2A (0.73) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL5975754 0.83 KMT2A (0.84) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL10819490 0.83 KMT2A (0.88) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL13490141 0.82 PTGS2 (0.58) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL10714367 0.82 KMT2A (0.74) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL9528544 0.82 KMT2A (0.86) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL7185321 0.81 KMT2A (0.70) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL924320 0.81 MAPT (1.00) KMT2AMEN1MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6582684-B1 A fluorescent and/or phosphorescent coating composition, particularly useful as a body coating, hair coating, lipstick and particularly as a phosphorescent nail polish that has the capability of changing from transparent, or other color, in XSIGHT INTERNATIONAL 2003-06-24 US disclosed