Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.50 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597910 | 0.80 | ANPEP (0.61) | FDPSANPEPERAP2MAPT | |
| SCHEMBL8991677 | 0.78 | ANPEP (0.64) | FDPSANPEPERAP2GAAMAPT | |
| SCHEMBL8675612 | 0.78 | ANPEP (0.64) | FDPSANPEPERAP2GAAMAPT | |
| SCHEMBL19350140 | 0.76 | FDPS (0.50) | FDPSANPEPERAP2GAAFAAH | |
| SCHEMBL8671774 | 0.73 | ANPEP (0.53) | FDPSANPEPERAP2MAPTGGPS1 | |
| SCHEMBL8672081 | 0.72 | MEN1 (0.41) | ANPEPERAP2MAPT | |
| SCHEMBL17397419 | 0.70 | MEN1 (0.39) | FDPSGAAFAAHPHGDHMGLL | |
| SCHEMBL14160640 | 0.67 | GAA (0.39) | GAAFAAHPHGDHMGLLMAPT | |
| SCHEMBL9124652 | 0.67 | GAA (0.39) | FDPSGAAFAAHPHGDHMGLL | |
| Thiomorpholinomethylenediphosphonic Acid SCHEMBL1471965 | 0.67 | FDPS (1.00) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248854-A1 | NOVEL BISPHOSPHONIC DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION. | LEO PHARM PROD LTD (DK) | 1987-12-16 | — | — | EP | disclosed |
| WO-1987003598-A1 | NOVEL BISPHOSPHONIC DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1987-06-18 | — | — | WO | disclosed |